Ionic or non-ionic contrast media in stent placement.

Induction of DNA damage, apoptosis and micronuclei in peripheral blood lymphocytes following injection of contrast media in patients with abdominal CT scan

Background: Medical diagnostic procedures such as X-ray and computed Tomography (CT) scan account for considerable percent of patient's exposure to ionizing radiation. The exposure of cells to Ionization radiation results in induction of DNA damage and chromosomal aberrations. Contrast media (CM) are widely used in diagnostic radiology and CT scan. The aim of this study was to study adverse gen...

The plight of the peer reviewer.

I read with interest the paper by Scheller et al., suggesting a better clinical outcome when patients undergoing percutaneous coronary intervention and stenting received an ionic contrast medium during the procedure than when non-ionic contrast media were used. These results are surprising since they completely disagree with the results of two randomized clinical trials comparing ionic and non-...

Influence of MRI contrast media on histamine release from mast cells

BACKGROUND Mast cells, owing to diversity of secreted mediators, play a crucial role in the regulation of inflammatory response. Together with basophils, mast cells constitute a central pathogenetic element of anaphylactic (IgE-dependent) and anaphylactoid (IgE-independent) reactions. In severe cases, generalized degranulation of mast cells may cause symptoms of anaphylactic shock. The influenc...

The development of non - ionic contrast media A cooperation between

Mixture of Ionic Liquids as Novel Media for Green Synthesis of Diketopyrrolopyrrole Pigments

A green method for the synthesis of high-performance diketopyrrolopyrrole pigments using diethyl succinate in the presence of mixture of ionic liquids is reported. Although, alkaline condition is needed in the succinate ester route for synthesis of the pigments, in the present study, the replacement possibility of conventional organic base by mixture of BMIMOH and BMIMBF4 ionic liquids was inve...